The Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) was developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer’s disease. It's language items were best for monitoring the progression of dementia. The Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog): Modifications and responsiveness in pre-dementia populations. Multiple regression analysis revealed that performance on the Korean ADAS- Cog was uninfluenced by age or gender, and neither by education level. ADAS-K-cog had high correlations with scores on the GDS (Pearson's r=0.732) and the Mini-Mental State Examination (Pearson's r=-0.755). The item score of orientation, expressive language, word finding difficulty, comprehension of spoken language and the ADAS-K-cog total score could classify severity of early AD patients efficiently. The total score of ADAS-K-cog and each item score differed significantly between each groups.
#ADAS COG TRIAL#
In the PD trial comparing rivastigmine and placebo, patients receiving rivastigmine had a mean improvement of 2.1 points in the ADAS-cog, whereas control. RESULTS: The subjects' age range was 65~93 years and their education range was 0~16 years. The ADAS-cog is a 70-point test with 11 parts (7 performance items and 4 clinician-rated items assessing memory, language, praxis, and orientation) and can take 3045 min to administer. The probable AD patients were divided into three groups based on their GDS stage to evaluate the sensitivity of ADAS-K-cog to disease severity and their mean scores on ADAS-K-cog were compared. Each patient was also rated on the Global Deterioration Scale (GDS). The ADAS-K-cog was administered to all AD subjects. METHODS: A total of 70 patients with AD meeting the NINCDS-ADRDA criteria of probable AD were recruited. Dive into the research topics of A study of the Alzheimers Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population. The version used in this study is the basic. We also studied the possible influence of age, sex, and education on a ADAS-K-cog. The ADAS-Cog is a commonly used objective measure of cognitive change. ABSTRACT BACKGROUND: This study was designed to examine the utility of the ADAS-Cog, Korean version (ADAS-K-cog) for staging of dementia in Alzheimer disease (AD).
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